Methodology of Estimation of Parameters in the Mechanism of Selecting Organizational and Technological Solutions

Purpose.The aim of this study is the substantiation of the methodology for assessing the choice parameters of the organizational and technological solutions, the selection mechanism is based on and determining the expediency of a particular decision regarding the priority MOR DHA PRENATAL of certain parameters within the integrated approach taking

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Pompe disease: from pathophysiology to therapy and back again

Pompe disease is a lysosomal storage disorder in which acid alpha-glucosidase is deficient or absent.Deficiency of this lysosomal enzyme results in progressive expansion of glycogen-filled lysosomes in multiple tissues, with cardiac and skeletal muscle being the most severely affected.The clinical spectrum ranges from fatal hypertrophic cardiomyopa

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